产品货号：
Z15001
中文名称：
CXCR3抗体
英文名称：
Anti-CXCR3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CXCR3 Antibody |
| 指标别名 | CD183;CKR L2;CMKAR3;CXC R3;CXCR 3;CXCR3;CXCR3A;CXCR3B;G protein coupled receptor 9;GPR9;IP 10 receptor;IP10 R;Mig R;MigR |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | IHC,WB |
| 基因名称 | CXCR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CXCR3 recombinant protein (Position:M1-L368).Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse and rat CXCR3. |
| 实际分子量 | 40～60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family.Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183.It is mapped to Xq13.1.CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders,particularly in patients with CLL,and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes.It is found that in the absence of known etiologic agents,CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes.CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG.CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1. |
| Uniprot ID | P49682 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | chemokine (C-X-C motif) receptor 3 |
| 蛋白名全称 | C-X-C chemokine receptor type 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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